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sufU [2019-04-18 10:28:32]
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sufU [2019-04-18 10:28:32]

sulfur shuttle protein, receives sulfur from [protein|88ACE6B79534338F7C72F107B35A0B2384007088|SufS], transfers it to [protein|5991F051C5BAD61A0860BBC64A37DB9D16130998|SufB]
locus
BSU32680
pI
4.71
mw
16.02 kDa
protein length
147 aa Sequence Blast
gene length
444 bp Sequence Blast
function
transfer of sulfur from [protein|search|SufS ]to [protein|5991F051C5BAD61A0860BBC64A37DB9D16130998|SufB]
product
sulfur shuttle protein
essential
yes
ec
2.-.-.-
synonyms
yurV,iscU
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.3|Biosynthesis of iron-sulfur clusters]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • Gene

    Coordinates
    3,357,011 → 3,357,454

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • the mutant is viable and Fe-S clusters are dispensable if [protein|search|IspG ]and [protein|search|IspH ]from the MEP pathway for isoprenoid biosynthesis are bypassed by a heterologous mevalonate pathway which allows B. subtilis to synthesize isopentenyl diphosphate and diphosphomevalonate [pubmed|29292548]

    • The protein

    Catalyzed reaction/ biological activity

  • transfer of sulfur from [protein|search|SufS ]to [protein|5991F051C5BAD61A0860BBC64A37DB9D16130998|SufB] [pubmed|29292548]

    • Protein family

  • nifU family (according to Swiss-Prot)

    • [SW|Cofactors]

  • zinc [Pubmed|24321018]

    • Structure

  • [PDB|2AZH]
  • [PDB|5XT5] (the [protein|88ACE6B79534338F7C72F107B35A0B2384007088|SufS]2-[protein|C0C30D2A6D3DF7A66063010044D370BD36D27DBF|SufU]2 complex) [pubmed|29235855]

    • Expression and Regulation

    Operons

    genes
    [gene|E966F3808222820C0644DC98F95765B89E6A2551|sufC]-[gene|1A9DA839AB77AF53958CB8426607BEF14F62B85E|sufD]-[gene|88ACE6B79534338F7C72F107B35A0B2384007088|sufS]-[gene|C0C30D2A6D3DF7A66063010044D370BD36D27DBF|sufU]-[gene|5991F051C5BAD61A0860BBC64A37DB9D16130998|sufB]
    description
    [Pubmed|22383849]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [pubmed|22383849], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B584 (yurV::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1583 NBRP B. subtilis, Japan]

    • References

    Reviews

  • 28882201

    • Original publications

  • 20087498,20097860,12682299,20233928,20822158,22383849,21236255,24321018,21744456,27382962,29235855,29292548